Structure-first design
Physical architecture is the experimental variable, not formulation or chemistry.
Applications
Where Structure Matters
BioECMCode™ products are designed for applications where extracellular structure, not formulation, is the dominant experimental variable. By providing fixed, reproducible extracellular architecture, our consumable platforms support a wide range of cell culture workflows without gels, coatings, or reactive chemistries.
Structured Cell Culture & Co-Culture Systems
BioECMCode™ enables structured culture environments where cells interact with defined physical architecture rather than bulk matrices. Applications include:
- Multi-cell culture systems requiring spatial organization
- Stromal–parenchymal interaction studies
- Layered or compartmentalized culture setups
- Long-term cultures requiring consistent extracellular structure
Architected plates and inserts allow researchers to introduce extracellular context while maintaining compatibility with standard culture workflows.
3D and 2.5D Culture Workflows
Many advanced culture models require structure beyond flat plastic, but without the variability of bulk gels. BioECMCode™ supports 2.5D and shallow 3D culture formats where architecture is fixed at manufacturing. Applications include:
- Structured 3D-like environments without gel handling
- Comparative studies across defined architectures
- Imaging-compatible structured cultures
- Screening workflows requiring uniform well-to-well structure
Mechanobiology & Physical Microenvironment Studies
BioECMCode™ products are well-suited for studies focused on physical cues, where geometry and surface topology influence cell organization and behavior. Applications include:
- Cell alignment and organization driven by structure
- Physical perturbation and architecture-dependent studies
- Comparative evaluation of different extracellular designs
- Experiments separating physical effects from chemical variables
Tumor Microenvironment & Stromal Interface Models
Tumor-associated studies often require structured extracellular context to examine interactions at tissue interfaces. BioECMCode™ provides reproducible extracellular architecture without reliance on gels or matrix formulations. Applications include:
- Tumor–stroma interface models
- Migration and invasion studies driven by structure
- Compartmentalized culture systems
- Screening platforms requiring consistent extracellular conditions
Drug Discovery & Screening Platforms
BioECMCode™ products integrate seamlessly into screening-scale workflows, enabling structured extracellular environments without compromising throughput. Applications include:
- Drug screening requiring standardized extracellular conditions
- Assays compatible with automation and liquid handling
- Reproducible multiwell formats for comparative studies
- Platforms where extracellular variability must be minimized
Why BioECMCode™ for Applications
Reagent-free consumables
No gels, coatings, or formulation-dependent preparation steps.
Manufactured reproducibility
Fixed extracellular structure across lots, users, and laboratories.
Workflow compatibility
Integrates into existing culture, imaging, and automation pipelines.
Design experiments around structure, not formulation.
Explore how BioECMCode™ applications enable reproducible extracellular environments across a wide range of cell culture workflows.