No polymerization
No gelation kinetics, curing time, or setting artifacts.
Technology
The BioECMCode™ Structural ECM Platform
The Problem with Conventional ECM Systems
Most extracellular matrix systems rely on soluble proteins, bulk gels, surface coatings, or reactive polymer systems that require user-controlled preparation. These approaches introduce experimental variability through:
- Protein concentration and dilution differences
- Polymerization or gelation kinetics
- Thickness, curing, and setting artifacts
- Operator handling, timing, and workflow variation
- Lot-to-lot material inconsistency
As a result, experimental outcomes often reflect ECM preparation variability rather than true biological differences.
The BioECMCode™ Approach
BioECMCode™ replaces formulation-based ECM systems with structurally encoded extracellular cultureware. Our products are:
- Pre-manufactured and ready-to-use
- Non-reactive and formulation-free
- Non-chemical by design
- Spatially defined at manufacturing
Cells interact with a fixed extracellular architecture that is consistent across lots, experiments, and laboratories, and independent of user handling or timing.
What “Structurally Encoded” Means
Instead of tuning extracellular behavior through chemistry, concentration, or polymerization, BioECMCode™ encodes extracellular instruction through physical architecture, including:
- Spatial geometry
- Surface topology
- Defined extracellular presentation
- Engineered 2D and 3D structures
This enables reproducible cell–environment interactions driven by structure rather than formulation.
What “Non-Chemical” Means
BioECMCode™ products require no polymerization, no crosslinking agents, and no formulation steps.
No tuning steps
No stiffness tuning or formulation-dependent workflows.
No reactive chemistry
No crosslinkers, ligand conjugation, or chemical coupling.
Open. Seed. Culture.
Benefits Summary
Structure-driven ECM control that simplifies workflows and improves reproducibility.
Reduced variability
Minimize operator-dependent and preparation-related variation across experiments.
Standardized workflows
Ready-to-use formats that reduce handling complexity and setup time.
Reproducibility at scale
Consistent extracellular architecture across lots, laboratories, imaging, and automation.
Contact us
Talk to our team for customized support